Coronial
ACThospital

Inquest Into The Circumstances Surrounding The Death Of Alex Nicholas Mersiades

Deceased

Alex Nicholas Mersiades

Demographics

3y, male

Date of death

1988-04-25

Finding date

1989-12-22

Cause of death

cerebral oedema which caused coning at the base of the brain, caused by post-operative hyponatraemia

AI-generated summary

A 3-year-old boy died from cerebral oedema caused by post-operative hyponatraemia following scoliosis correction surgery. The operation was successful, but severe hyponatraemia developed in the early hours of 24 April 1988, causing cerebral oedema and brain herniation. Death occurred 25 April 1988. The coroner found the death was caused by failure to monitor serum sodium levels post-operatively. Despite extensive published literature on hyponatraemia as a post-operative complication (particularly after scoliosis surgery in children), the surgical and anaesthetic teams were unaware of this risk. The coroner recommended that future scoliosis operations should include daily serum sodium monitoring with appropriate corrections. Once the seizure occurred, brain damage was irreversible.

AI-generated summary — refer to original finding for legal purposes. Report an inaccuracy.

Specialties

surgeryanaesthesiapaediatrics

Error types

diagnosticdelay

Contributing factors

  • failure to monitor serum sodium levels post-operatively
  • lack of awareness of hyponatraemia risk following scoliosis correction surgery despite published literature

Coroner's recommendations

  1. Future scoliosis correction operations should be followed by simple daily monitoring of serum sodium levels, with corrections if appropriate
Full text

''1l1il1~~~mi11~~Mjf' 054084

IN THE CORONERS COURT ) AT CANBERRA IN ) CD 52/88 AUSTRALIAN CAPITAL TERRITORY ) INQUEST INTO 'I'HE CIRCUMSTANCES SURROUNDING THE DEATH OF ALEX NICHOLAS MERSIADES Alex Mersiades was born on 12th November 1984. He died at about 8.30 a.m. on 25th April 1988. Death was caused 'by cerebral oedema which caused coning at the base of the brain. That is to say, the brain had swollen into the lower portion of the cranial cavity. The swelling was caused by excessive fluid. The probable cause of the cerebral oedema was post-operative hypnotremia. Hyponatremia is a low level of sodiwn in the blood. Hyponatremia is a complication which can follow surgery of many kinds, on different people. There is, by now, a considerable volume of literature on the subject. Some of the titles include: ·' Hyponatremia . . . after elective surgery in heal thy women (Exhibit 5).

Hyponatremia ... in outpatients.

Hyponatremia in acute polyneuropathy.

Severe hyponatremia in hospital patients.

The outcome of hyponatrernia in a general hospital population.

Inappropriate secretion of anti-diuretic hormone after open heart surgery.

Inappropriate secretion of anti-diuretic hormone in post surgical pediatric population (Exhibit 6).

~

t ... Severe hyponatremia in the elderly.

i I Inappropriate anti-diuretic hormone secretion in post operative adolescent spinal fusion patients (from Scoliosis Research Society 17th Annual Meeting) .

.· Anti diuretic hormone secretion in cardiac surgical patients.

Inappropriate anti diuretic hormone secretion.in the orthopedic patient.

~1 These, and many, many other articles highlight the dangers of hyponatremia in the following cases, amongst J. others: .i after surgery ~ ~ after surgery on children 0.

after surgery correcting scoliosis on children.

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j Finally, and after Alex's death, the paper: Hyponatremia following correction of scoliosis in ~hildren.

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Alex was aged a little over 3 ; at the time. He '1(' was admitted to the John James Hospital for surgery to correct a scoliosis i.e. a curvature of the spine. He underwent the ~ operation on 22nd April 1988. The operation itself was .

0, uneventful and successful. However, in the early hours of the morning of 24th April 1988, Alex suffered the cerebral oedema.

t°'E Subsequent testing showed he had a sodium level below sc,~rum the critical level. The autopsy showed clearly enough that he '.Zl died from cerebral oedema. It is an almost inescapable

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conclusion that Alex died because his serum sodium level fell too far after the operation.

J: !lJ The surgeon and the anaesthetist say, and I accept this, that they were unaware of the possibility of any such a q complication. In view of the considerable volume of 'q .-~---~:~.e:nr.~=------------------

·_:: ,~-/: li1 literature on the subject, I have some difficulty accepting this. However, the co-author of the most specific article ("Hyponatremia following correction of scoliosis in children", Dr Carroll) says that this was so. Few surgeons, and anaesthetists and hospitals in Australia, he said, are aware of the danger of hyponatremia following operations to correct scoliosis in children. Whether this evidence be true or not, or whether the fact be that the dange:cs of hyponatremia are well known and documented, not only as set out in the above literature,· but also in the cases documented under the heading "Water Intoxication" in Mann's "Medical Negligence Litigation", is a matter I am unable to determine. That will have to be left to the judgement of Dr McNicholl and Dr Flynn's peers.

')<" 'li( It is to be hoped that similar operations in future will be followed by simple daily monitoring of serum sodium h levels, with corrections if appropriate.

~ I find that the lack of a resident medical officer :,1 at the hospital had no bearing on the death. The death was :0, caused by a failure to monitor .the serum sodium levels. Once Alex suffered the fit in the early hours of the morning of it 25th April 1 I 988, the brain damage was irreversible. The i nursing care was quite adequate. In any event, the doctors 7.. i : arrived at the scene quite quickly after the event.

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ML.Ward Coroner '.:t.'( 'lo.

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. I Coroners Ordinance 1956-1967

INQUISITION BEFORE A CORONER SITTING ALONE AUSTRALIAN CAPITAL TERRITORY CANBERRA TO WIT INQUISITION held at the Law Courts of the Australian Capital Territory, City, Canberra in the Australian Capital Territory on the Twenty-second day of December in the year One Thousand Nine Hundred and Eighty:..nine before me, MICHAEL WARD Esquire, one of the Coroners of our Sovereign Lady the Queen for the Territory as to the manner and cause of death of ALEX NICHOLAS MERSIADES AND I such Coroner being charged to inquire (on the part of our said Lady the Queen) when, where, how and by what means the said ALEX NICHOLAS MERSIADES came to death declare and find that ALEX NICHOLAS MERSIADES died on the Twenty-£ if th day of March in the year One Thousand Nine Hundred and Eighty-eight at Royal Canberra Hospital, Acton in the Australian Capital Territory from cerebral oedema which caused coning at the base of the brain.

IN WITNESS whereof, I the said Coroner, have to this INQUISITION set my hand this day and year aforesaid.

~R Prin<N by Au1horiry by 1hc Commonwealth Government Prin1er. Canberra

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